As part of a major research consortium announced last June, the UK’s top scientists have discovered that some seabirds are demonstrating immunity to avian influenza.
The FluMap consortium, headed by the world-leading research team at the Animal Plant Health Agency (APHA), has developed laboratory tools that can dissect the immune response in birds that have been exposed to avian influenza viruses in their lifetime.
Preliminary investigations in a small sample size of some species of seabird, including Northern gannets and Shag, revealed specific immunity to H5N1 showing exposure and recovery in a proportion of birds. However, avian influenza viruses are prone to change and so antibody levels will likely decline over time with next year’s offspring not guaranteed to be immune suggesting there are no great population level benefits yet.
The consortium has also identified several genetic characteristics that explain the ability of the current H5N1 viruses to spread fast and infect a greater range of species. Research has found that multiple virus genes have switched and evolved to act together to enhance fitness to infect, transmit and persist in birds, but remain un-adapted to humans.
The consortium has mapped the spread of infection over time and made important discoveries regarding airborne transmission of the virus – determining that infectious virus can only travel short distances (less than 10 metres) and is very unlikely between farms through the air.
Scientists hope to look at the effect of antibodies on infection, to better predict the emergence of new viruses with different protein combinations in the future, allowing experts to stay one step ahead to safeguard animal and human health, given 60% of new human diseases originate in animals.
You can read more in the full press release which also provides a link to the research.